4-Benzyloxy-3,5-dimethylphenylboronic acid

4-Benzyloxy-3,5-dimethylphenylboronic acid - Names and Identifiers

Name	4-Benzyloxy-3,5-dimethylphenylboronic acid
Synonyms	4-Benzyloxy-3,5-dimethylphenylboronic acid [4-(Benzyloxy)-3,5-dimethylphenyl]boronic acid (3,5-dimethyl-4-phenylmethoxyphenyl)boronic acid Boronic acid, B-[3,5-dimethyl-4-(phenylmethoxy)phenyl]-
CAS	333788-94-6
InChI	InChI=1/C15H17BO3/c1-11-8-14(16(17)18)9-12(2)15(11)19-10-13-6-4-3-5-7-13/h3-9,17-18H,10H2,1-2H3

4-Benzyloxy-3,5-dimethylphenylboronic acid - Physico-chemical Properties

Molecular Formula	C15H17BO3
Molar Mass	256.1
Density	1.15±0.1 g/cm3(Predicted)
Melting Point	220-222°C
Boling Point	443.9±55.0 °C(Predicted)
Flash Point	222.2°C
Vapor Presure	1.17E-08mmHg at 25°C
pKa	8.82±0.18(Predicted)
Storage Condition	2-8°C
Refractive Index	1.579

4-Benzyloxy-3,5-dimethylphenylboronic acid - Risk and Safety

Hazard Symbols

C - Corrosive

4-Benzyloxy-3,5-dimethylphenylboronic acid - Introduction

4-Benzyloxy-3,5-dimethylphenylboronic acid, also known as 4-Benzyloxy-3,5-dimethylphenylboronic acid, belongs to organic boron compounds. Here are some of its properties, uses, methods, and safety information:

Nature:
-Appearance: White or light yellow crystalline powder.
-Melting point: about 175-180 ° C.
-Solubility: Soluble in ethanol, dimethyl ether and chloroform, but insoluble in water.

Use:
- 4-Benzyloxy-3,5-dimethylphenylboronic acid is an important intermediate in organic synthesis and is often used as a boron reagent in organic synthesis reactions. It can be borated with an organic halide or sulfonate to produce the corresponding borate compound. These borate compounds play an important role in metal-catalyzed carbon-carbon bond formation reactions, such as Suzuki coupling reactions, Stile coupling reactions, etc.

Method:
-The synthesis of 4-Benzyloxy-3,5-dimethylphenylboronic acid is usually obtained by reacting Phenylboronic acid with iodophenyl ethane under alkaline conditions. The specific synthesis method can refer to the relevant organic synthesis literature or patent.

Safety Information:
-The specific safety information of 4-Benzyloxy-3,5-dimethylphenylboronic acid should be determined according to the safety data sheet provided by the specific chemical supplier to ensure correct and safe use. Generally speaking, these chemicals may be irritating to the eyes, skin and respiratory tract, so appropriate personal protective measures are required during operation, such as wearing protective glasses, laboratory clothing and gloves, ensure that the operating environment is well ventilated, etc. At the same time, it should be kept away from fire and oxidant, stored in a dry, cool place. If you have any questions or unexpected situations, please seek professional help immediately.

Last Update：2024-04-09 21:11:58